February 16 – Nepal Airlines Flight 183, a de Havilland Canada DHC-6, crashes near Khidim about 74 kilometres southwest of Pokhara, Nepal, killing all 18 people on board.
February 17 – Ethiopian Airlines Flight 702, a Boeing 767, is hijacked by the co-pilot while en route from Addis Ababa, Ethiopia, to Rome, Italy, but lands safely at Geneva, Switzerland. All 202 passengers and crew aboard are unharmed.
March 8 – Malaysia Airlines Flight 370, a Boeing 777 en route from Kuala Lumpur to Beijing with 227 passengers and 12 crew on board, disappears from radar over the Gulf of Thailand.
July 17 – Malaysia Airlines Flight 17, a Boeing 777 en route from Amsterdam to Kuala Lumpur, is shot down over eastern Ukraine, killing all 283 passengers and 15 crew on board in the deadliest civilian airliner shootdown incident.
July 23 – TransAsia Airways Flight 222, an ATR-72 en route from Kaohsiung to Penghu, Taiwan, crashes during go-around, killing 48 of the 58 people on board.
July 24 – Air Algérie Flight 5017, a chartered Swiftair McDonnell Douglas MD-83 operating for Air Algérie en route from Burkina Faso to Algiers, crashes in the northern Mali desert after disappearing from radar approximately 50 minutes after takeoff, killing all 112 passengers and 6 crew members on board.
August 10 – Sepahan Airlines Flight 5915, a HESA IrAn-140 (an Antonov An-140 built under license) crashes shortly after takeoff from Mehrabad International Airport, Iran, killing 39 of the 48 people on board.
December 28 – Indonesia AirAsia Flight 8501, an Airbus A320 en route from Surabaya, Indonesia to Singapore with 155 passengers and 7 crew on board, crashes into waters off Borneo.